It has been shown that oleuropein has a direct antioxidant effect on skin, due to its free radical scavenging action at the skin level. Treatment of human embryonic fibroblasts with oleuropein was found to decrease the intracellular levels of reactive oxygen species (ROS). These cells exhibited a delay in senescence and had a fifteen percent (15%) increased lifespan.
Oleuropein has many pharmacological properties that aid in the protection of skin cells. It is antimicrobial, it slows the progress of cell aging, protects the skin from environmental stress including chronic UV B radiation-induced skin damage, and it is a potent anti-inflammatory agent.